Product Bioprocess Consumables Storage and Transfer of Bioprocessing Fluid Closed Systems

Closed System for Centrifuge Tubes/Bottles

* Specifications of matching tubes/bottles: 50 mL 250 mL 500 mL
* Type of tube connector: MLL connector
* Specifications of matching tubing: Two-port
* Packaging: Double-layer outer medical packaging

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Introduction

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Introduction

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In the industrial production of biological products, reducing the potential risk of contamination during processes such as liquid transfer and sampling is crucial. Pairing centrifuge tubes with sterile transfer caps and tubing systems can effectively prevent contamination issues associated with open operations.
Jet Biofil has introduced a Closed System for Centrifuge Tubes/Bottles, made from USP Class VI compliant materials, manufactured in GMP-standard cleanrooms, and subjected to rigorous tests including extractables studies and biocompatibility assessments. These systems are suitable for enclosed sampling and aseptic liquid transfer in bioprocessing. It comes with double-layer packaging, and each system is equipped with a separately packaged plug seal cap, which can be replaced for supporting subsequent operations , such as centrifugation and testing.

Customization Service

Jet Biofil offers an extensive library of fully validated components including vessels, filters, connectors, tubing, clamps, and plugs making it easy to design a customized closed system solution for your specific application

Inner tube can be extended to the bottom to ensure complete transfer

Tubing length and diameter can be customized according to specific needs

0.22µm PTFE syringe filter balances the internal and external pressure during liquid transfer while maintaining sterility

Injection molded bottle cap sharply decrease leakage and residue

Features

* Raw materials compliant with USP Class VI standards, products feature extremely low extractable levels and excellent biosafety
* Injection molded bottle cap sharply decrease leakage and residue
* Inner tube can be extended to the bottom to ensure complete transfer
* 0.22µm PTFE syringe filter balances the internal and external pressure during liquid transfer while maintaining sterility
* Separately packaged plug seal cap can be replaced for supporting subsequent operations , such as centrifugation and testing
* Tubing length and diameter can be customized according to specific needs
* Working temperature range: -80~60℃
* Sterilized by irradiation, SAL 10^-6; DNase/RNase-free, non-pyrogenic, non-cytotoxic

Material

* Bottle cap (HDPE) Inner tube (PTFE) Outer thermoplastic tube (TPE) MLL connector (PP) Filter housing (PP) Filter membrane(PTFE)
* Conforming to USP Class VI standards

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Brochure

Closed System Series for Aseptic Transfers

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Catalogue

Jet Biofil ENG Catalogue 2025

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Order Information

Cat. No.	Product Name	Tubing Specification			Filter	Sterile	Extra Component	Qty. Per Bag	Qty. Per Case
Cat. No.	Product Name	Tubing Type	Tubing Dimension	Tubing Connector	Filter	Sterile	Extra Component	Qty. Per Bag	Qty. Per Case
CST010050	Closed System for 50mL Centrifuge Tube	Two-port	50cm, 1/8" ID, 1/4" OD	MLL	0.22μm，PTFE,φ30mm	Y	Each closed system comes with a plug seal cap for replacement	1	4
CST010250	Closed System for 250mL Conical Bottle	Two-port	50cm, 1/8" ID, 1/4" OD	MLL	0.22μm，PTFE,φ30mm	Y		1	4
CST010500	Closed System for 500mL Conical Bottle	Two-port	50cm, 1/8" ID, 1/4" OD	MLL	0.22μm，PTFE,φ30mm	Y		1	4

MLL male Luer connector with plug